# Regenerative Medicine > Stem cell and exosome therapy at Hygeia, focused on cellular health, repair and recovery. What the therapies are, how a course runs, and why it starts with a consult. specialty therapy Advanced Cellular + Regenerative Therapies Idledale, Colorado | Denver Foothills Regenerative medicine is an evolving field focused on cellular health, communication and the biological processes involved in repair, recovery and resilience. At Hygeia, regenerative medicine is approached intentionally. We begin by understanding your health history, goals and foundations before determining whether an advanced regenerative therapy has a place in your [personalized wellness plan](https://ozoneandalternativetherapies.com/treatments/personalized-wellness/). [Start Your Regenerative Medicine Journey→](https://ozoneandalternativetherapies.com/treatments/regenerative-medicine/#journey) [Book a 15-Minute Clarity Call→](https://app.malla.co/join/holly-deffert-10501/quick-clarity-call-15-minutes) ## Your Regenerative Medicine Journey Start With a KUREwave BioAnalysis + Deep Dive Consultation: $525 Before moving into regenerative medicine, I want to understand the bigger picture. We begin with your health history, current concerns, goals and foundations, along with a KUREwave BioAnalysis to help us explore patterns and areas that may deserve a closer look. I then bring everything together during your Deep Dive consultation so we can create a personalized roadmap and determine whether regenerative therapy, and which approach, makes sense for you. ### Your $525 Investment Goes With You If you decide to move forward with a Hygeia regenerative treatment package or protocol, your $525 KUREwave + Deep Dive investment will be applied toward that plan. In other words, the consultation isn't an extra expense on top of your regenerative program. It's where we begin. [Book KUREwave + Deep Dive: $525→](https://bioanalysis.kurebioclinic.com/bioanalysis-booking) [Not sure where to start? Book a 15-Minute Clarity Call.](https://app.malla.co/join/holly-deffert-10501/quick-clarity-call-15-minutes) ## What Are MSCs? Mesenchymal Stem Cells MSCs are specialized cells extensively studied in regenerative medicine for their unique biological and signaling properties. What makes MSCs particularly interesting is their ability to communicate with their surrounding cellular environment. They release growth factors, cytokines and extracellular vesicles that participate in cell-to-cell signaling and other biological processes. Rather than thinking of MSCs simply as cells that "replace" damaged tissue, modern regenerative research increasingly focuses on their role as signaling cells and the complex ways they interact with other cells. ### Why Are MSCs Special? Cellular Communication MSCs release signaling molecules that communicate with surrounding cells. Growth Factors + Cytokines MSCs secrete numerous biologically active signaling factors. Extracellular Vesicles MSCs release microscopic vesicles involved in transferring biological information between cells. Regenerative Research Their unique cellular and signaling biology has made MSCs an important area of regenerative medicine research. ## What Are Exosomes? Tiny Messengers Between Cells Exosomes are nanosized extracellular vesicles released by cells. They carry biological information, including proteins, lipids and genetic material, and are one of the ways cells communicate with one another. If MSCs are the cells, exosomes can be thought of as part of their messaging system. This ability to carry signaling information between cells is one reason exosomes have become such an active area of regenerative medicine research. MSCs + Exosomes MSCs The cells Cellular signaling Communication between cells Exosomes Part of the cellular messaging system Together, MSCs and exosomes help illustrate the extraordinary complexity of cellular communication being explored in regenerative medicine. ## Regenerative Medicine at *Hygeia* Regenerative medicine represents some of the most sophisticated and elegant therapies I work with. What fascinates me about this field is the intelligence of cellular communication. We aren't simply talking about replacing a vitamin, mineral or nutrient. We're entering the incredibly complex world of cells, signaling molecules and the ways cells communicate with one another. That's also why I don't believe these therapies should be approached as one-size-fits-all treatments. I want to understand you first, your history, your foundations, what your body has been through, what you're experiencing now and what you're ultimately trying to accomplish. From there, we can determine whether regenerative medicine belongs in your plan and what the most intentional path forward looks like. ## Advanced Regenerative Options at Hygeia ### Cellular Regenerative Therapy Advanced cellular therapies considered within the context of your individual health history, goals and overall regenerative plan. ### Exosome-Based Regenerative Therapy Cell-free regenerative approaches centered around extracellular vesicles and cellular signaling. ### Inhaled Regenerative Support Select regenerative options may be incorporated through alternative routes of administration when appropriate to the individualized plan. ## Why Clients Explore Regenerative Medicine ### Cellular Health ### Recovery + Resilience ### Energy + Vitality ### Mobility + Physical Function ### Healthy Aging + Longevity ### Whole-Body Wellness Regenerative medicine is an evolving field of science and research. Individual responses vary, and no specific outcome can be guaranteed. Whether a regenerative therapy is appropriate depends on the individual, the specific product being considered and relevant clinical factors. ### Commonly used for Concerns clients have sought Living Cells therapy to support. Listing them is not a claim that it treats, prevents, or cures any condition. - Anti-Aging - Mitochondria Regeneration - Symptoms of arthritis & joint pain - Injuries from sports or accidents - Peripheral neuropathy - Energy levels & performance - Muscle strength & tone - Hair regrowth - Skin tone & facial appearance - Symptoms of sexual dysfunction ## How We Approach Regenerative Care 01 ### Assess Understand your history, goals, foundations and current health picture. 02 ### Build the Foundation Identify areas that may need attention before layering in advanced therapies. 03 ### Treat Intentionally Determine whether regenerative medicine belongs in your plan and which approach makes sense. 04 ### Measure + Reassess Continue evaluating your progress and adjust the larger wellness plan when appropriate. Who Leads Your Care? Holly Deffert, RN Holly is a registered nurse with 16 years of nursing experience, including 14 years in emergency medicine, and the founder of Hygeia. Her practice focuses on [medical ozone and O3UV therapy](https://ozoneandalternativetherapies.com/treatments/ozone-o3uv/), advanced IV therapy, regenerative wellness, cellular health and longevity. Holly has completed specialized regenerative medicine education through Dr. Joy Kong's American Academy of Integrative Cell Therapy (AAICT), with education in stem cell science, regenerative therapies, clinical protocols, safety considerations and cellular medicine. She personally works with each client, combining her clinical background with a research-informed, whole-person approach and collaborating with appropriately licensed healthcare providers when needed. Personalized care. Advanced wellness. A nurse who takes the time to look deeper. [Book a 15-Minute Clarity Call→](https://app.malla.co/join/holly-deffert-10501/quick-clarity-call-15-minutes) ## Questions to ask before choosing regenerative therapy Ask these of any clinic, including this one. Here are our answers. ### 01 Who will perform my treatment and what are their credentials? At Hygeia Wellness, your IV and regenerative treatments are personally performed by Holly Deffert, RN, a registered nurse with 16 years of nursing experience, including 14 years in emergency medicine. Holly specializes in medical ozone therapy, O3UV, advanced IV therapies, [PolyMVA](https://ozoneandalternativetherapies.com/treatments/polymva/), [NAD+](https://ozoneandalternativetherapies.com/treatments/vitamin-drips/), nutritional IV therapy, and regenerative cellular therapies. Hygeia also operates with medical oversight. When a treatment requires medical evaluation, clearance, prescribing, or provider orders, an appropriately licensed medical provider is involved. ### 02 How many patients with my condition have you treated? Hygeia does not treat clients based solely on a diagnosis or place every person with the same condition into the same protocol. Your health history, symptoms, previous treatments, current medications, lifestyle, goals, functional assessment findings, and available laboratory data are reviewed individually. Holly will be transparent about her experience with clients who have similar health concerns and will refer or collaborate with another provider when something falls outside her scope or expertise. ### 03 What outcomes are realistic for me specifically? There is no responsible way to guarantee a specific outcome from regenerative therapy. The goal is to identify what you are hoping to improve: such as energy, recovery, mobility, joint function, cognition, resilience, or overall quality of life: and determine whether regenerative therapy may reasonably support that goal. Expectations are discussed before treatment, including what the therapy may support, what it cannot promise, and how progress will be evaluated. Individual responses vary. ### 04 How is the product sourced and handled? Hygeia uses regenerative products obtained through established professional suppliers and follows the manufacturer’s required procedures for storage, handling, preparation, and administration. Product information, including the specific product being used, is reviewed as part of the treatment process. Hygeia takes sourcing, handling, sterility, and appropriate clinical administration seriously and encourages clients to ask questions about any regenerative product before receiving treatment. ### 05 What is included in the quoted price? Pricing is reviewed before treatment so you understand what is included. Depending on the treatment or program, pricing may include the regenerative product, IV administration, nursing care, supportive IV fluids or adjunct therapies, treatment-day monitoring, aftercare instructions, and scheduled follow-up. If additional therapies, laboratory testing, consultations, or follow-up services are recommended, those costs are discussed separately unless they are specifically included in your program or membership tier. ### 06 What does follow-up look like? Regenerative care is not viewed as a single treatment followed by “see you later.” Hygeia uses structured follow-up to evaluate how you are responding over the following weeks and months. Depending on your goals, this may include tracking symptoms, energy, sleep, mobility, pain, physical function, quality of life, laboratory markers, functional assessments, or biological-age testing. Your plan may evolve based on what your body is actually doing: not simply according to a predetermined schedule. ### 07 What are the risks and contraindications? Every therapy has potential risks, limitations, precautions, and situations in which it may not be appropriate. Your medical history, medications, allergies, previous reactions, current health status, and relevant risk factors are reviewed before treatment. When additional medical evaluation or clearance is necessary, Hygeia involves or refers to an appropriately licensed provider. Potential risks and aftercare considerations are discussed before treatment so that you can make an informed decision. ### 08 Would you tell me if I were not a candidate? Absolutely. Being offered the most expensive or most advanced therapy is not automatically the best answer. Sometimes the appropriate next step is improving foundational health, completing additional testing, addressing another issue first, obtaining medical clearance, or working with a different specialist. Hygeia’s goal is to recommend therapies intentionally: not simply because they are available. ### 09 How do you measure results? Before treatment, we identify what you are actually trying to change. Depending on your goals, progress may be evaluated through: - Symptoms and quality-of-life changes - Energy and recovery - Sleep - Mobility and physical function - Pain or joint function - Cognitive or neurological symptoms - Laboratory markers - Functional assessments - Body composition or metabolic markers - Biological-age testing when appropriate The purpose is to create a baseline whenever possible and then reassess rather than relying only on subjective impressions. ### 10 Can I speak with a physician before booking? Hygeia Wellness is led by Holly Deffert, RN, not a physician. Your initial consultation and health-optimization process are conducted with Holly within her professional scope as a registered nurse. Hygeia operates with medical oversight, and when your treatment requires medical evaluation, diagnosis, prescribing, medical clearance, or provider orders, an appropriately licensed medical provider is involved. If your situation requires evaluation by a physician or another specialist, Holly will recommend referral rather than attempting to manage something outside her scope. Hygeia's Philosophy Regenerative medicine should not begin with the assumption that everyone needs the most advanced therapy. We begin by understanding the whole picture. Assess. Build the foundation. Treat intentionally. Measure. Reassess. Depending on the individual, the larger plan may include nutrition and lifestyle changes, targeted testing, detoxification support, O3UV, IV nutrition, NAD+, PolyMVA, regenerative therapies or collaboration with other healthcare providers. This information is provided for educational purposes and is not intended to diagnose, treat, cure, or prevent disease. Hygeia Wellness does not guarantee outcomes from regenerative or other therapies. Individual responses vary. Medical diagnosis, prescribing, and medical decision-making are performed by appropriately licensed providers when required. Important Information Regenerative medicine is an evolving area of science and medicine. Products may differ in their source, composition, processing, regulatory status and supporting evidence. Individual responses vary, and regenerative therapies are not presented as guaranteed treatments or cures. Relevant health history, medications, potential risks, contraindications and clinical considerations are reviewed before treatment. ## What *clients* say about regenerative therapy Honest words from clients who worked through a regenerative plan with Holly. Holly told me to fix my foundation before we talked about cells. Six months later the plan looked completely different, and so did I. Karen M. Conifer, CO The follow-up is the part I did not expect. Someone actually checked on how I was doing at week six. Tom B. Morrison, CO I asked every hard question on that list. She answered all of them without selling me anything. Andrea P. Genesee, CO Individual results vary. Client experiences are shared with permission and are not a promise of outcome. ## Ready to Explore Regenerative Medicine? Start with a conversation. We'll talk about where you are, what you're hoping to accomplish and whether regenerative medicine may have a place in your overall wellness plan. [Start With KUREwave + Deep Dive: $525→](https://bioanalysis.kurebioclinic.com/bioanalysis-booking)[Book a 15-Minute Clarity Call→](https://app.malla.co/join/holly-deffert-10501/quick-clarity-call-15-minutes) If you move forward with a Hygeia regenerative treatment package or protocol, your $525 KUREwave + Deep Dive investment will be applied toward your plan. [Questions? Text 720-240-1360](sms:7202401360)