our signature therapy

Medical Ozone + Ultraviolet Light Idledale, Colorado

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O3UV is for people who want to be proactive about their health, supporting overall wellness, vitality, recovery, and healthy aging, as well as those navigating more complex or chronic health concerns.

For clients with chronic or more complex health concerns, Holly recommends starting with a 90-Minute Deep Dive Consultation ($350) and/or KUREwave BioAnalysis. This allows Holly to look at the bigger picture, understand your health history and goals, and develop a more personalized roadmap before determining which therapies may be appropriate for your plan.

Ozone therapy is not FDA-approved to diagnose, prevent, treat, or cure any disease, and results vary from person to person.

One of our lovely patients receiving O3UV, already on her way to feeling so much better.

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O3UV combines medical ozone with ultraviolet blood irradiation (UVBI) in one blood-based therapy.

During treatment, a measured amount of blood is drawn into a closed system, where it is exposed to a carefully controlled concentration of medical ozone and specific wavelengths of ultraviolet light before being returned to your circulation.

Why combine ozone + UV light?

Medical ozone and ultraviolet blood irradiation have each been studied independently for their effects on oxidative signaling, cellular processes, and immune response. O3UV brings these two modalities together in a single treatment.

At Hygeia, your protocol is individualized based on your health history, goals, and overall wellness plan.

Think of O3UV as cellular support, not a cure or a one-size-fits-all treatment.

Not sure whether O3UV or High-Dose O3UV is right for you? Holly can help you determine an appropriate starting point based on your health history, goals, and overall wellness plan.

Your O3UV experience begins with a brief check-in so we can review how you're feeling and determine the appropriate protocol for you.

During treatment, blood is drawn into a closed system, exposed to a precise concentration of medical ozone and ultraviolet light, and then returned to your circulation. Depending on your individualized protocol, treatment volume and appointment length may vary.

O3UV: approximately 45–60 minutes.
High-Dose O3UV: approximately 1.5–2 hours.
Treatment times are approximate and may vary.

Most clients simply relax, read, work, or rest during their session.

How many sessions will I need?

The number of O3UV sessions varies depending on your goals, health history, and individual response. A single session is available for clients who want to experience O3UV before committing to a series.

For clients pursuing a more comprehensive protocol, Hygeia offers packages of 5 and 10 treatments. Clients may begin with a 5-treatment package and add an additional five treatments when appropriate.

Frequency and protocol can be adjusted along the way based on your individual response and overall wellness plan.

Commonly used for

Concerns clients have sought ozone and O3UV therapy to support. Listing them is not a claim that it treats, prevents, or cures any condition.

At Hygeia, your care is personal from beginning to end. Holly Deffert, RN, personally performs your O3UV treatments, giving you consistency with someone who knows your history, your goals, and how you've responded along the way.

With 16 years of nursing experience, including 14 years in emergency medicine, and a passion for integrative and regenerative wellness, Holly brings clinical experience together with a deeply individualized approach to care.

O3UV can stand alone or become part of a bigger wellness strategy incorporating advanced testing, IV therapies, nutrition, detoxification support, and regenerative medicine when appropriate.

Located in the Denver foothills, Hygeia serves Idledale, Evergreen, Morrison, Golden, Conifer, Genesee, and surrounding communities.

No assembly-line wellness. No one-size-fits-all protocols. Just thoughtful, personalized care and a plan built around you.

kind words

★★★★★★★★★★ 14 weeks ago

Nurse Holly of Hygeia delivered expert care for the healing of my severe cellulitis infection of my leg. I received both ozone and vitamin C infusions that greatly helped speed and complete my healing & recovery. Thank you so much!

★★★★★★★★★★ 6 weeks ago

I came in for O3UV after months of feeling wiped out and getting nowhere with my regular doctor. Holly explained every step, never oversold anything, and by the third session I was sleeping through the night again.

★★★★★★★★★★ 3 months ago

I do a maintenance O3UV every few weeks now. It is the one thing I have kept up for a year, because I can feel the difference when I skip it. Holly tracks everything and adjusts as we go.

Holly Deffert is a registered nurse with 16 years of nursing experience, including 14 years in emergency medicine, and the founder of Hygeia Wellness.

Her practice focuses on medical ozone and O3UV therapy, regenerative medicine and stem cell therapies, NAD+, advanced IV therapies, cellular health, and longevity.

Holly personally works with each client, combining her clinical background with a research-informed, root-cause approach to create individualized wellness strategies. She also collaborates with naturopathic, functional-medicine, and holistic providers when appropriate to support the bigger picture of each client's health.

Personalized care. Advanced wellness. A nurse who takes the time to look deeper.